Bioinformatics | Oncology | Pathology Cross-modal integration of bulk RNA-seq and single-cell RNA sequencing data to reveal T-cell exhaustion in colorectal cancer. September 30, 2024
Immunology | Neurology | Psychiatry Permethrin exposure primes neuroinflammatory stress response to drive depression-like behavior through microglial activation in a mouse model of Gulf War Illness. September 13, 2024
Bioinformatics | Computational Biology | Genomics CellContrast: Reconstructing spatial relationships in single-cell RNA sequencing data via deep contrastive learning. September 5, 2024
Cardiology | Oncology STdGCN: spatial transcriptomic cell-type deconvolution using graph convolutional networks. August 5, 2024
Genomics | Nephrology | Oncology | Pathology Single-cell sequencing reveals novel proliferative cell type: a key player in renal cell carcinoma prognosis and therapeutic response. July 25, 2024
Bioinformatics | Genomics SFINN: inferring gene regulatory network from single-cell and spatial transcriptomic data with shared factor neighborhood and integrated neural network. July 1, 2024
Neurology | Psychiatry Short tandem repeat expansions in cortical layer-specific genes implicate in phenotypic severity and adaptability of autism spectrum disorder. May 16, 2024
Bioinformatics | Genetics | Oncology CopyVAE: a variational autoencoder-based approach for copy number variation inference using single-cell transcriptomics. April 27, 2024
Multiomics | Nephrology | Pathology Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury. April 2, 2024
Oncology | Pathology Image-based profiling and deep learning reveal morphological heterogeneity of colorectal cancer organoids. March 30, 2024
Bioinformatics | Genomics | Oncology Deep neural network learning biological condition information refines gene-expression-based cell subtypes. January 17, 2024
Bioinformatics | Gastroenterology | Immunology | Pathology Single-cell dissection, hdWGCNA and deep learning reveal the role of oxidatively stressed plasma cells in ulcerative colitis. October 10, 2023