Oncology | Pharmacology Discovery of novel Akt1 inhibitors by an ensemble-based virtual screening method, molecular dynamics simulation, and in vitro biological activity testing. January 19, 2024
Bioinformatics | Cell Biology | Genetics Unveiling human origins of replication using deep learning: accurate prediction and comprehensive analysis. November 26, 2023
Oncology | Pharmacology Combination of QSAR Modeling and Hybrid-Based Consensus Scoring to Identify Dual-Targeting Inhibitors of PLK1 and p38γ. October 26, 2023
Oncology | Pharmacology XMR: an explainable multimodal neural network for drug response prediction. August 21, 2023
Immunology | Oncology A distinct stimulatory cDC1 subpopulation amplifies CD8 T cell responses in tumors for protective anti-cancer immunity. July 14, 2023
Bioinformatics | Computational Biology | Oncology KR4SL: knowledge graph reasoning for explainable prediction of synthetic lethality. June 30, 2023
Bioinformatics | Oncology | Pharmacology SYNDEEP: a deep learning approach for the prediction of cancer drugs synergy. April 15, 2023
Clinical Research | Drug Development | Oncology Patient-derived xenograft models in cancer therapy: technologies and applications. April 12, 2023
Computational Biology | Oncology | Pharmacology A systematic evaluation of deep learning methods for the prediction of drug synergy in cancer. March 23, 2023
Oncology | Pharmacology QSAR modeling and molecular docking studies of 2-oxo-1, 2-dihydroquinoline-4- carboxylic acid derivatives as p-glycoprotein inhibitors for combating cancer multidrug resistance. February 7, 2023
Computational Biology | Oncology Computational methods, databases and tools for synthetic lethality prediction. March 30, 2022
Data Science | Oncology | Pharmacology Prediction of synergistic drug combinations using PCA-initialized deep learning. October 21, 2021