Biochemistry | Biotechnology Engineering a Robust UDP-Glucose Pyrophosphorylase for Enhanced Biocatalytic Synthesis via ProteinMPNN and Ancestral Sequence Reconstruction. June 26, 2024
Bioinformatics | Dermatology | Pharmacology A Top-Down Design Approach for Generating a Peptide PROTAC Drug Targeting Androgen Receptor for Androgenetic Alopecia Therapy. June 5, 2024
Bioinformatics | Immunology | Protein Design Exploring the Potential of Structure-Based Deep Learning Approaches for T cell Receptor Design. May 7, 2024
Biotechnology Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. March 19, 2024
Bioinformatics | Computational Biology | Protein Engineering An integrative approach to protein sequence design through multiobjective optimization. March 18, 2024
Biochemistry | Enzyme Engineering | Structural Biology Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination. February 15, 2024
Bioinformatics | Protein Design ProteinMPNN Recovers Complex Sequence Properties of Transmembrane β-barrels. February 14, 2024
Bioinformatics | Structural Biology Transfer learning to leverage larger datasets for improved prediction of protein stability changes. January 29, 2024
Bioinformatics | Oncology | Protein Engineering In silico evolution of autoinhibitory domains for a PD-L1 antagonist using deep learning models. November 30, 2023
Biotechnology | Structural Biology Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. August 14, 2023
Biochemistry | Molecular Biology Robust Design of Effective Allosteric Activators for Rsp5 E3 Ligase Using the Machine Learning Tool ProteinMPNN. August 9, 2023
Bioinformatics | Protein Engineering evolution of protein binders with deep learning models for structure prediction and sequence design. May 19, 2023