Bioinformatics | Structural Biology Knot or not? Identifying unknotted proteins in knotted families with sequence-based Machine Learning model. June 18, 2024
Drug Development | Neurology | Pharmacology Delta-Conotoxin Structure Prediction and Analysis through Large-scale Comparative and Deep Learning Modeling Approaches. June 10, 2024
Bioinformatics | Neurology | Structural Biology Insights into AlphaFold’s breakthrough in neurodegenerative diseases. June 4, 2024
Other HighFold: accurately predicting structures of cyclic peptides and complexes with head-to-tail and disulfide bridge constraints. May 6, 2024
Molecular Biology | Reproductive Medicine Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse. April 26, 2024
Bioinformatics | Immunology Can AlphaFold’s breakthrough in protein structure help decode the fundamental principles of adaptive cellular immunity? April 23, 2024
Biochemistry | Biotechnology Predicting the Structure of Enzymes with Metal Cofactors: The Example of [FeFe] Hydrogenases. April 13, 2024
Bioengineering | Protein Design Protein Design Using Structure-Prediction Networks: AlphaFold and RoseTTAFold as Protein Structure Foundation Models. March 4, 2024
Biochemistry | Molecular Biology Assessment of machine-learning predictions for the Mediator complex subunit MED25 ACID domain interactions with transactivation domains. March 4, 2024
Biochemistry | Molecular Biology Substrate recognition principles for the PP2A-B55 protein phosphatase. February 19, 2024
Oncology A revised molecular model of ovarian cancer biomarker CA125 (MUC16) enabled by long-read sequencing. January 10, 2024
Computational Chemistry | Drug Development | Pharmaceutical Sciences DrugHIVE: A Deep Hierarchical Variational Autoencoder for the Structure-Based Design of Drug-Like Molecules. January 8, 2024